SILICOFCM consortium had the Third plenary meeting in London, UK, 25-26 November 2019, at the Royal Society of Medicine, organized by Newcastle University (www.ncl.ac.uk). The progress of project activities, integrated within 11 Work Packages, was presented during the meeting. SILICOFCM partners had the opportunity to discuss with Advisory Board members, prof. Petros Malitas, prof. Paolo Vicini and prof. David Brodie. Interesting topics and discussions, active participation of all attendees and setting of common plans for further period of the project made this meeting a very successful.